Methods To address this issue we analyzed CD4+ T absolute counts and the proportion of CD8+ T cells expressing CD38 in Leishmania/ HIV co-infected patients that recovered after anti-leishmanial therapy. This might contribute to impaired cellular immune function. We investigated whether leishmaniasis increases lymphocyte activation in HIV- 1 co-infected patients. In the Americas, visceral (AVL and tegumentary leishmaniasis (ATL have emerged as important opportunistic infections in HIV-AIDS patients and both of those diseases have been implicated as potentially important co-factors in disease progression. High levels of T lymphocyte activation in Leishmania- HIV- 1 co-infected individuals despite low HIV viral loadĭirectory of Open Access Journals (Sweden)įull Text Available Abstract Background Concomitant infections may influence HIV progression by causing chronic activation leading to decline in T-cell function.
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